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Infants born to HBsAg-negative mothers:

• Dose 1: by age 2 months
• Dose 2:  1 month after the 1st dose
• Dose 3:  at least 4 months after 1st dose and at least 2 months
  after the 2nd dose, but not before 6 months of age.

Infants born to HBsAg-positive mothers:

• Dose 1:  within 12 hrs of birth with 0.5mL hepatitis B immune globulin (HBIG)
• Dose 2:  1-2 months of age
• Dose 3:  6 months of age.

Infants born to HBsAg-unknown mothers:

• Dose 1:  within 12 hrs of birth.  
• Mother's blood should be tested to determine HBsAg status.  If maternal HBsAg is positive, the infant should receive HBIG as soon as possible (no later than 1 week of age).  Follow above schedule.

All children and adolescents:

• Should begin the series during any visit.  
• Follow the 1st schedule for the 2nd and 3rd doses regardless of age.

4th Dose:

• May be administered as early as 12 months, provided 6 months have elapsed since 3rd dose and the child is unlikely to return at 15-18 months of age.

Td:

• Recommended at 11-12 years of age if at least 5 years have elapsed since the last dose of DTP, DTap, or DT.
• Td boosters should be administered every 10 years.

3 Hib vaccines are licensed for infant use.

• If PRP-OPM (PevaxHIB® or ComVax® [Merck]) is given at 2 and 4 months of age, a dose at 6 months is not required.

DTaP/Hib combination products should not be used for primary immunization in infants at 2, 4, or 6 months of age, unless FDA-approved for these ages

• Because clinincal studies in infants have demonstrated that using some combination products may induce a lower immune response to the Hib vaccine component.

All children should receive 4 doses of IPV

• 2 months
• 4 months
• 6-18 months
• 4-6 years

Oral Polio Vaccine (OPV) should be used only in selected circumstances

• see MMWR May 19,2000/49(RR-5);1-22)

The heptavalent conjugate pneumococcal vaccine (PVC) is recommended for:

• all children 2-23 months of age
• certain children 24-59 months of age (see MMWR Oct. 6,2000/49(RR-9);1-35)

The second dose of measles, mumps, and rubella (MMR) vaccine is recommended at 4-6 years of age, but may be administered during any visit, provided:

• at least 4 weeks have elapsed since the 1st dose  AND
• both doses are administered at or after 12 months of age

Those who have not received the 2nd dose should complete the schedule by the 11-12 year old visit.

Recommended at any visit at or after 12 months of age
Required for daycare, preschool, school age children

• 07/01/2001: required for any child in daycare or preschool (in FL)
• 09/01/2001: required of all children in Kindergarten (in FL)

Susceptible persons 13 years of age or older should receive:

• 2 doses, at least 4 weeks apart

Hepatitis is recommended for:

• selected states and/or regions
• certain high risk groups
• see MMWR Oct. 1,1999/48(RR-12);1-37)

For additional information, visit the National Immunization Program